(R)-(+)-1,1'-联(2-萘酚)

It is used in biosynthetic preparation for enantioselective oxidation of naphthols to binaphthyldiols with horseradish peroxidase catalyst. A chiral auxiliary used in the catalytic asymmetric oxidation of sulfides to sulfoxides. Chiral lanthanide triflates formed from binaphthol serve as catalysts for asymmetric Diels-Alder reactions. Derivatives of binaphthol have recently found use in asymmetric Claisen rearrangements and asymmetric epoxidations.5 The lithium aluminum hydride derivative of these diols (BINAP-H) has been used extensively for the reduction of ketones. Chiral binapthol imminium salt precursor. Salts were used for an asymmetric epoxidation of olefins.

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

MFCD00004068

C₂₀H₁₄O₂

286.33

206-211°

1.301

Ambient temperatures.

Crystalline powder

Insoluble in water. Solubility in THF within almost transparency). Soluble in dioxane 50 mg/mL.

3616837

14,1226

III

25-36/37/38
Toxic if swallowed.Irritating to eyes, respiratory system and skin.

6.1

26-36/37-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

DU3106100

否

 

H301-H315-H319-H335
Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P280h-P305+P351+P338-P309-P310
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.