1,3-二氯-1,1,3,3-四异丙基二硅氧烷

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3'- and 5'-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.

Incompatible with strong oxidizing agents and water.

MFCD00009655

000-000-0

C₁₂H₂₈Cl₂OSi₂

315.43

69-70°/0.5mm

>110°(230°F)

0.986

1.4540

Moisture Sensitive. Ambient temperatures.

Miscible with dimethylformamide, hexane, ethyl acetate, chloroform and dichloromethane.

1934216

II

34
Causes burns.

8

20-26-36/37/39-45
When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

 

否

 

H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.

P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.