5-氟尿嘧啶

5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen's disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor.

Store in a cool place. Incompatible with strong oxidizing agents and strong bases.

MFCD00006018

200-085-6

C₄H₃FN₂O₂

130.08

ca 282° dec.

Light Sensitive. Ambient temperatures.

Crystalline powder

Soluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.

127172

14,4181

III

61-22-48/22-68
May cause harm to the unborn child.Harmful if swallowed.Harmful: danger of serious damage to health by prolonged exposure if swallowed.Possible risk of irreversible effects.

6.1

53-45
Avoid exposure - obtain special instructions before use.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

YR0350000

是

  

H302-H341-H360-H373
Harmful if swallowed.Suspected of causing genetic defects.May damage fertility or the unborn child.May cause damage to organs through prolonged or repeated exposure.

P260-P201-P280-P301+P312a-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray.Obtain special instructions before use.Wear protective gloves/protective clothing/eye protection/face protection.Wear protective gloves/protective clothing/eye protection/face protection.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.