2-碘乙酰胺

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.

MFCD00008028

205-630-1

ICH₂CONH₂

184.96

92-95°(dried)

Keep Cold. Light Sensitive.

Crystalline solid

Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

1739080

III

25-36/37/38-43
Toxic if swallowed.Irritating to eyes, respiratory system and skin.May cause sensitization by skin contact.

6.1

24-26-37-45
Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

AC4200000

是

 

H301-H315-H319-H317-H335
Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.May cause respiratory irritation.

P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.