无水乳清酸

Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

Stable under recommended storage conditions. Incompatible with oxidizing agents.

MFCD00006027

200-619-8

C₅H₄N₂O₄

156.10

344-347°

Ambient temperatures.

Powder

Slightly soluble in water.

22-36/38
Harmful if swallowed.Irritating to eyes and skin.

26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

RM3180000

 

是

 

H302-H315-H319
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.

P280a-P305+P351+P338-P301+P312a-P321-P332+P313-P501a
Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment (see label).If skin irritation occurs: Get medical advice/attention.Dispose of contents/container in accordance with local/regional/national/international regulations.