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CP-802079 hydrochloride hydrate

产品编号:3072673
规格:≥98% (HPLC)
CAS NO:736175-49-8
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
30726735 MG1570
307267325 MG5470
产品别名

736175-49-8

CP-802079 hydrochloride hydrate

({3-(4-Chlorophenyl)-3-[4-(thiazole-carbonyl)-phenoxy]-propyl}-methyl-amino)-acetic acid hydrochloride hydrate

N-[3-(4-Chlorophenyl)-3-[4-(2-thiazolylcarbonyl)phenoxy]propyl]-N-methyl-glycine hydrochloride hydrate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C22H21ClN2O4S · xHCl · yH2O
Molecular weight
444.93 (anhydrous free base basis)
MDL number
MFCD18452850
PubChem Substance ID【PubChem化学物质编号】
329823733
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
CP-802079 is a potent and selective glycine transporter type 1 (GlyT1) antagonist. Antagonists of GlyT1 increase levels of glycine in the synaptic cleft and, like direct glycine site agonists, they can augment NMDAR currents and NMDAR-mediated functions. CP-802,079 significantly increases the amplitude of the NMDAR currents and LTP.
Features and Benefits【特点和优势】
This compound is featured on the Glycine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes【其他说明】
This compound was developed by Pfizer for Neuroscience research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information【法律信息】
Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
manufacturer/tradename
Pfizer®
color【颜色】
very light brown
solubility【溶解性】
DMSO: ≥20 mg/mL
originator【创始人】
Pfizer
storage temp.【储存温度】
2-8℃
SMILES string
O.Cl.CN(CCC(Oc1ccc(cc1)C(=O)c2nccs2)c3ccc(Cl)cc3)CC(O)=O
InChI
1S/C22H21ClN2O4S.ClH.H2O/c1-25(14-20(26)27)12-10-19(15-2-6-17(23)7-3-15)29-18-8-4-16(5-9-18)21(28)22-24-11-13-30-22;;/h2-9,11,13,19H,10,12,14H2,1H3,(H,26,27);1H;1H2
InChI key
CVQXAUBKPDYXHF-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H315 - H319 - H335
Precautionary Statements
P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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