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CyPPA
| 产品编号： | 3073752 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 73029-73-9 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3073752 | 5 MG | 1530 | |||
| 3073752 | 25 MG | 7790 |
产品别名
73029-73-9
CyPPA
Cyclohexyl-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-amine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H23N5 |
| Molecular weight | 285.39 |
| MDL number | MFCD01550586 |
| PubChem Substance ID【PubChem化学物质编号】 | 329775087 |
| NACRES | NA.77 |
| Application【应用】 | CyPPA has been used:
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| Biochem/physiol Actions【生化/生理作用】 | CyPPA is a positive modulator of small conductance Ca2+-activated K+ channels; selective for SK3 and SK2. CyPPA is a first subtype selective SK channel positive modulator with an EC50 of 5.6 μM and 14 μM, efficacy 90% and 71% for hSK3 and hSK2, respectively. CyPPA is a tool for distinguishing SK2 and SK3 from SK1 and IK; no other agents distinguish these channels. |
| Features and Benefits【特点和优势】 | This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: >10 mg/mL H2O: <2 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cc1cc(NC2CCCCC2)nc(n1)-n3nc(C)cc3C |
| InChI | 1S/C16H23N5/c1-11-10-15(18-14-7-5-4-6-8-14)19-16(17-11)21-13(3)9-12(2)20-21/h9-10,14H,4-8H2,1-3H3,(H,17,18,19) |
| InChI key | USEMRPYUFJNFQN-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 - H413 |
| Precautionary Statements | P273 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
