葡聚糖酶 来源于Chaetomium erraticum

3.2.1.11 ( BRENDA | IUBMB )

232-803-9

MFCD00130940

NA.54

Dextranase is generated by many microorganisms, including bacteria, filamentous fungi, and yeast.
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Dextranase from Chaetomium erraticum has been used:

• in microcarrier dissolution to produce multicellular 3D spheroids for drug discovery
• in in vitro digestion of extracellular polysaccharide (EPS) from the bacterial isolates
• in a study to investigate the immobilization of dextranase
• to investigate the optimization of process conditions for enzymatic modification of alternan

Dextranase is an endodextranase that hydrolyzes α-(1,6)-glycosidic linkages in dextran. It has many industrial and clinical applications such as food processing, sugar modification, and medicine preparation. Dextranase is widely used to produce alternated sugar beet and isomaltooligosaccharides (IMOs), a prebiotic functional food. The low molecular weight dextran obtained from dextranase serves as a synthetic blood volume expander. Dextranase can be coupled to antibodies for the detection of tumor cells. It prevents the occurrence of dental plaques by depolymerizing microbial dextran deposits in teeth. Hence, it is used in dental care products.

通过Chaetomium erraticum的深层发酵产生的一种真菌葡聚糖酶。

在pH 3-7范围内以及最高约70 ℃的温度下稳定。对于绝大多数应用，比较适合的条件是pH 5-6且 50-60 ℃的温度。

更多关于复杂碳水化合物分析酶的信息请见www.sigma-aldrich.com/enzymeexplorer

300

solution

2-8℃

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)