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DPPE hydrochloride
产品别名
92981-78-7
DPPE hydrochloride
[2-(4-Benzyl-phenoxy)-ethyl]-diethyl-amine hydrochloride
BMS-217380-01
YMB1002
N,N-Diethyl-2-[4-(phenylmethyl) phenoxy]ethanamine hydrochloride
Tesmilifene hydrochloride
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C19H25NO·HCl |
Molecular weight | 319.87 |
MDL number | MFCD11114012 |
PubChem Substance ID【PubChem化学物质编号】 | 329798745 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | DPPE is a potent, selective ligand of the microsomal anti-estrogen binding site. DPPE is a tamoxifen derivataive that binds with high affinity to the anti-estrogen binding site, but unlike tamoxifen, does not bind to the estrogen receptor. DPPE sensitizes MDR tumor cells to chemotherapy and also inhibits histamine binding at the intracellular histamine site. |
Features and Benefits【特点和优势】 | This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white |
solubility【溶解性】 | H2O: 16 mg/mL |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | Cl.CCN(CC)CCOc1ccc(Cc2ccccc2)cc1 |
InChI | 1S/C19H25NO.ClH/c1-3-20(4-2)14-15-21-19-12-10-18(11-13-19)16-17-8-6-5-7-9-17;/h5-13H,3-4,14-16H2,1-2H3;1H |
InChI key | TXLHNFOLHRXMAU-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | nwg |