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Ethyl arachidonate
产品别名
1808-26-0
Ethyl arachidonate
5,8,11,14-Eicosatetraenoic acid ethyl ester
Arachidonic acid ethyl ester
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H36O2 |
| Molecular weight | 332.52 |
| MDL number | MFCD00038340 |
| PubChem Substance ID【PubChem化学物质编号】 | 24891398 |
| NACRES | NA.25 |
| Biochem/physiol Actions【生化/生理作用】 | Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation. AA is subsequently metabolized to prostaglandins and thromboxanes by at least two cyclooxygenase (COX) isoforms, to leukotrienes and lipoxins by lipoxygenases, and to epoxyeicosatrienoic acids via p450-catalyzed metabolism. AA and its metabolites play important roles in a variety of biological processes, including signal transduction, contraction, chemotaxis, and cell proliferation, differentiation and apoptosis. AA has been demonstrated to bind to the α subunit of G protein and inhibit the activity of Ras GTPase-activating proteins (GAPs). Cellular uptake of AA is energy dependent and involves protein-facilitated transport across the plasma membrane. |
产品性质
| biological source【生物来源】 | fungus |
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98.5% (GC) |
| form【形式】 | liquid |
| functional group【官能团】 | ester |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC |
| InChI | 1S/C22H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h8-9,11-12,14-15,17-18H,3-7,10,13,16,19-21H2,1-2H3/b9-8-,12-11-,15-14-,18-17- |
| InChI key | SNXPWYFWAZVIAU-GKFVBPDJSA-N |
| packaging【包装】 | 10, 100, 500 mg in ampule 1 g in ampule Sealed ampule. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves |
