广州伟伯科技有限公司
您的位置:首页 > 产品中心 > 5104-49-4, 氟比洛芬
产品搜索:

氟比洛芬

Flurbiprofen
产品编号:3088213
规格:Pharmaceutical Secondary Standard; Certified Reference Material
CAS NO:5104-49-4
包装规格:500 MG
产品类别:进口试剂
品牌:Supelco
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3088213500 MG1190
产品别名

5104-49-4

氟比洛芬

Flurbiprofen

L-790,330

(±)-2-Fluoro-α-methyl-4-biphenylacetic acid

(±)-2-氟-α-甲基-4-联苯基乙酸

结构式
基本信息
Linear Formula【线性分子式】
C6H5C6H3(F)CH(CH3)CO2H
Molecular weight
244.26
EC number【EC 号】
225-827-6
MDL number
MFCD00079303
PubChem Substance ID【PubChem化学物质编号】
329823420
NACRES
NA.24
General description【一般描述】
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Flurbiprofen is a non-selective, non-steroidal anti-inflammatory drug (NSAID) that is widely used against rheumatoid arthritis. It is also effective against vernal keratoconjunctivitis, post-operative ocular inflammation, herpetic stromal keratitis, excimer laser photorefractive keratectomy and ocular gingivitis.
Application【应用】
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Flurbiprofen may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and biological samples by various analytical techniques.
Biochem/physiol Actions【生化/生理作用】
Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.
Analysis Note【分析说明】
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes【其他说明】
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote【附注】
To see an example of a Certificate of Analysis for this material enter LRAA3047 in the slot below. This is an example certificate only and may not be the lot that you receive.
产品性质
Quality Level【质量水平】
300
grade【等级】
certified reference material
pharmaceutical secondary standard
CofA
current certificate can be downloaded
packaging【包装】
pkg of 500 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
110-112 ℃ (lit.)
application(s)
pharmaceutical (small molecule)
format【格式】
neat
pharmacopeia traceability【药典可追溯性】
traceable to PhEur F0285200
traceable to USP 1285750
storage temp.【储存温度】
2-30℃
SMILES string
CC(C(O)=O)c1ccc(c(F)c1)-c2ccccc2
InChI
1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
InChI key
SYTBZMRGLBWNTM-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742), PTGS2(5743)
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0085