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Fmoc-(R)-2-(7-octenyl)Ala-OH
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3088428 | 1 G | 2180 | |||
| 3088428 | 5 G | 9450 |
产品别名
945212-26-0
Fmoc-(R)-2-(7-octenyl)Ala-OH
Fmoc-(R)-2-(7-octenyl)alanine
Fmoc-(R)-2-amino-2-methyl-dec-6-enoic acid
(R)-N-Fmoc-α-(7-Octenyl)alanine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H31NO4 |
| Molecular weight | 421.53 |
| MDL number | MFCD12925761 |
| PubChem Substance ID【PubChem化学物质编号】 | 329799756 |
| NACRES | NA.26 |
| Application【应用】 | Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake. |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | solid |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| application(s) | peptide synthesis |
| functional group【官能团】 | Fmoc |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)N[C@@](CCCCCCC=C)(C)C(O)=O |
| InChI | 1S/C26H31NO4/c1-3-4-5-6-7-12-17-26(2,24(28)29)27-25(30)31-18-23-21-15-10-8-13-19(21)20-14-9-11-16-22(20)23/h3,8-11,13-16,23H,1,4-7,12,17-18H2,2H3,(H,27,30)(H,28,29)/t26-/m1/s1 |
| InChI key | MADFVGMQNXRFAF-AREMUKBSSA-N |
| packaging【包装】 | 1, 5 g in glass bottle |
安全信息
| Pictograms【象形图】 | GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H400 |
| Precautionary Statements | P273 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
