福辛普利 钠

C₃₀H₄₅NO₇P · Na

585.64

MFCD23704184

329799677

NA.77

Fosinopril lowers blood pressure and functions as an antihypertensive agent. It is an ester prodrug. Fosinopril is metabolised by the liver and excreted from the body by liver and kidney. It is used to treat heart failure.

Fosinopril is an angiotensin converting enzyme (ACE) inhibitor. Fosinopril is also known to inhibit the activity of the peptide transporter PEPT2.

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

100

≥98% (HPLC)

powder

desiccated

white to off-white

H₂O: >20 mg/mL

Bristol-Myers Squibb

−20℃

O=C([O-])[C@H]1N(C(CP(CCCCC2=CC=CC=C2)(O[C@@H](C(C)C)OC(CC)=O)=O)=O)C[C@H](C3CCCCC3)C1.[Na+]

1S/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30+,39?;/m1./s1

TVTJZMHAIQQZTL-TXDYNIFHSA-M

5, 25 mg in glass bottle

GHS07,GHS08

Warning

H319 - H361d

P202 - P264 - P280 - P305 + P351 + P338 - P308 + P313 - P337 + P313

Eye Irrit. 2 - Repr. 2

11 - Combustible Solids

WGK 3