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GLYX-13 trifluoroacetate
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3091797 | 1 MG | 2300 |
产品别名
117928-94-6
GLYX-13 trifluoroacetate
TPPT-amide trifluoroacetate
Rapastinel
L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate; Thr-Pro-Pro-Thr-NH2 trifluoroacetate
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C18H31N5O6 · xC2HF3O2 |
Molecular weight | 413.47 (free base basis) |
MDL number | MFCD20527320 |
PubChem Substance ID【PubChem化学物质编号】 | 329825164 |
NACRES | NA.77 |
Application【应用】 | GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor. |
Biochem/physiol Actions【生化/生理作用】 | GLYX-13 is a glycine-site functional partial agonist (GFPA) selective modulator of the NMDA receptor (NMDAR). It is a brain penetrable tetrapeptide which acts as a positive allosteric modulator of the NMDA receptor, acting via the glycine site. GLYX-13 has been found to be a cognitive enhancer in learning models and is currently in clinical trials as an antidepressant. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to tan |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | OC(=O)C(F)(F)F.C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H]([C@@H](C)O)C(N)=O |
InChI | 1S/C18H31N5O6.C2HF3O2/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26;3-2(4,5)1(6)7/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27);(H,6,7)/t9-,10-,11+,12+,13+,14+;/m1./s1 |
InChI key | BCWVNVCGYWOAAK-GDLIIDCZSA-N |
packaging【包装】 | 1 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |