Goat anti-DBC1/p30 DBC Antibody, Affinity Purified

NA.41

The epitope recognized by PLA0305 maps to a region between residue 873 to 923 of human p30 DBC Protein using the numbering given in entry NP_066997.3 (GeneID 57805).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

The DBC1 (Deleted in Breast Cancer Gene 1 protein) gene is located in a region frequently deleted in breast cancers. In its uncleaved form, DBC1 is localized to the nucleus. Upon cleavage by caspase activity, DBC1 becomes localized to the cytoplasm and functions to promote apoptosis. DBC1 has also been found to bind directly to the estrogen receptor alpha (ERalpha) hormone binding domain to modulate ERalpha expression and mediate hormone-independent breast cancer cell survival.

100

goat

affinity purified immunoglobulin

primary antibodies

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human, mouse

1 mg/mL

immunohistochemistry: 1:2,000-1:5,000
immunoprecipitation (IP): 2- 10 μg/mg
western blot: 1:2,000-1:10,000

NP_066997.3

wet ice

2-8℃

human ... CCAR2(57805)

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12 - Non Combustible Liquids

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