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Guanosine 5′-diphosphate disodium salt
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3094144 | 100 MG | 2460 | |||
| 3094144 | 500 MG | 7770 |
产品别名
7415-69-2
Guanosine 5′-diphosphate disodium salt
5′-GDP-Na2
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H13N5Na2O11P2 |
| Molecular weight | 487.16 |
| EC number【EC 号】 | 231-026-2 |
| MDL number | MFCD00084665 |
| PubChem Substance ID【PubChem化学物质编号】 | 57651304 |
| NACRES | NA.51 |
| General description【一般描述】 | Guanosine 5′-diphosphate (GDP) is a purine nucleotide and is interconvertible to guanosine by the action of ectonucleotidases and by nucleoside phosphorylase into guanine. GDP is majorly acted upon by 5′‐ectonucleotidases in neuronal cells. |
| Application【应用】 | Guanosine 5′-diphosphate disodium salt has been used:
Guanosine 5′-diphosphate (GDP) is used as a substrate of pyruvate kinase to produce GTP in support of RNA biosyntheis. GDP is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). GDP is also used to study cell signaling processes mediate by guanine nucleotide exchange factors. |
| Biochem/physiol Actions【生化/生理作用】 | Guanosine based nucleosides play a key role in multiple cellular processes and generation growth factors. Elevated levels of guanosine 5′-diphosphate (GDP) is associated with the pathogenesis of neurological disorders. GDP is bound to G protein . G protein coupled receptors (GPCRs) activate G proteins by exchanging the bound GDP to GTP. GDP is potent inhibitor agent of hepcidin- ferroportin complex and may be effective for promoting erythropoiesis and treating anemia of inflammation(AI). |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | Porcine brain microbial (Corynebacterium sp) synthetic |
| Assay【测定】 | ≥90% (HPLC) |
| form【形式】 | powder |
| solubility【溶解性】 | H2O: 50 mg/mL, clear, colorless |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | [Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1 |
| InChI | 1S/C10H15N5O11P2.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1 |
| InChI key | LTZCGDIGAHOTKN-LGVAUZIVSA-L |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
