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Idazoxan hydrochloride

产品编号:3098033
CAS NO:79944-56-2
包装规格:50 MG,100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
309803350 MG1590
3098033100 MG1600
产品别名

79944-56-2

Idazoxan hydrochloride

(±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride

RX 781094

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C11H12N2O2 · HCl
Molecular weight
240.69
MDL number
MFCD00069293
PubChem Substance ID【PubChem化学物质编号】
24278493
NACRES
NA.77
Application【应用】
Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.
Biochem/physiol Actions【生化/生理作用】
α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).
产品性质
Quality Level【质量水平】
100
solubility【溶解性】
H2O: 50 mg/mL
SMILES string
Cl.C1CN=C(N1)C2COc3ccccc3O2
InChI
1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H
InChI key
MYUBYOVCLMEAOH-UHFFFAOYSA-N
Gene Information
human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)
安全信息
Pictograms【象形图】
GHS06
Signal word【警示用语:】
Danger
Hazard Statements
H301
Precautionary Statements
P301 + P310
Hazard Classifications【危险分类】
Acute Tox. 3 Oral
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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