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IL-36γ mouse
产品编号: | 3098338 |
规格: | recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE) |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
IL-36γ mouse
Interleukin-36γ
Interleukin-1 family member 9
SSI-3
基本信息
NACRES | NA.32 |
General description【一般描述】 | IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. |
Physical form【外形】 | Lyophilized from PBS and 0.5% trehalose. |
Reconstitution【重悬】 | Reconstitute with 100 μL deionized water. |
Other Notes【其他说明】 | IL-36gamma (mouse) (aa 13-164) is untagged. |
产品性质
biological source【生物来源】 | mouse |
recombinant【重组】 | expressed in E. coli |
conjugate【偶联物】 | untagged |
Assay【测定】 | >95% (SDS-PAGE) |
form【形式】 | lyophilized |
mol wt【分子量】 | ~17 kDa |
packaging【包装】 | pkg of 10 μg |
impurities【杂质】 | <0.01 EU/μg endotoxin, tested |
color【颜色】 | white |
UniProt accession no.【UniProt登记号】 | Q8R460 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... Il36g(215257) |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |