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Lazabemide hydrate

产品编号:3104576
规格:≥97% (HPLC)
CAS NO:103878-84-8
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
310457610 MG1032
310457650 MG3600
产品别名

103878-84-8

Lazabemide hydrate

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrate

Ro 19-6327 hydrate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C8H10ClN3O · xH2O
Molecular weight
199.64 (anhydrous basis)
MDL number
MFCD20488051
PubChem Substance ID【PubChem化学物质编号】
329825112
NACRES
NA.77
Application【应用】
Lazabemide hydrate may be used in cell signaling studies.
Biochem/physiol Actions【生化/生理作用】
Lazabemide is effective in treatment of Alzheimer′s disease and in combination with nicotine replacement therapy aids in smoking cessation.
Lazabemide is a selective and reversible monoamine oxidase B (MAO-B) inhibitor and Anti-Parkinson. Also it inhibits monoamine uptake at high concentrations (IC50 values are 86, 123 and > 500 μM for noradrenalin, serotonin and dopamine uptake respectively).
Features and Benefits【特点和优势】
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥97% (HPLC)
form【形式】
powder
storage condition【储存条件】
desiccated
color【颜色】
white to tan
solubility【溶解性】
DMSO: ≥22 mg/mL
originator【创始人】
Roche
storage temp.【储存温度】
room temp
SMILES string
O.NCCNC(=O)c1ccc(Cl)cn1
InChI
1S/C8H10ClN3O.H2O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10;/h1-2,5H,3-4,10H2,(H,11,13);1H2
InChI key
JYWYNPKXSLPWGV-UHFFFAOYSA-N
packaging【包装】
10, 50 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H319
Precautionary Statements
P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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