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LY2033298
产品别名
LY2033298
3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methyl-thieno[2,3-b]pyridine-2-carboxamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H14ClN3O2S |
| Molecular weight | 311.79 |
| MDL number | MFCD12912423 |
| PubChem Substance ID【PubChem化学物质编号】 | 329817677 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | LY2033298 is a robust allosteric potentiator that is highly selective for the human M4 muscarinic acetylcholine receptor subtype. LY2033298 potentiates ACh-M4 binding, with no effect at M1/3/5 receptors. LY2033298 can also bind to the M ACh receptor, and mediate either positive or negative allosteric effects depending on the ligand used to probe receptor activity. |
| Features and Benefits【特点和优势】 | This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | off-white to tan |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| originator【创始人】 | Eli Lilly |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl |
| InChI | 1S/C13H14ClN3O2S/c1-5-7-9(15)10(11(18)16-6-3-4-6)20-13(7)17-12(19-2)8(5)14/h6H,3-4,15H2,1-2H3,(H,16,18) |
| InChI key | CTEGQKDJTBWFHW-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H334 |
| Precautionary Statements | P261 - P284 - P501 |
| Hazard Classifications【危险分类】 | Resp. Sens. 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
