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1-Naphthylacetyl spermine trihydrochloride
产品别名
1-Naphthylacetyl spermine trihydrochloride
NASPM trihydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H34N4O · 3HCl |
| Molecular weight | 479.91 |
| MDL number | MFCD01321052 |
| PubChem Substance ID【PubChem化学物质编号】 | 24897539 |
| NACRES | NA.77 |
| Application【应用】 | 1-Naphthylacetyl spermine trihydrochloride has been used for the inhibition of calcium-permeable AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). It has also been used to study the involvement of AMPAR in biphasic activation of stress-activated protein kinase/extracellular signal-regulated kinase-1. |
| Biochem/physiol Actions【生化/生理作用】 | Blocks Ca2+ permeable AMPA receptor channels. |
| Other Notes【其他说明】 | Synthetic analog of Joro spider toxin. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | H2O: ≥20 mg/mL |
| SMILES string | Cl.Cl.Cl.NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12 |
| InChI | 1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H |
| InChI key | JNEOJAUJWOPWJS-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
