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2-乙酰胺基丙烯酸甲酯
Methyl 2-Acetamidoacrylate
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3110396 | 5 G | 1920 |
产品别名
35356-70-8
2-乙酰胺基丙烯酸甲酯
Methyl 2-Acetamidoacrylate
结构式
基本信息
| Linear Formula【线性分子式】 | H2C=C(NHCOCH3)CO2CH3 |
| Molecular weight | 143.14 |
| MDL number | MFCD00013394 |
| PubChem Substance ID【PubChem化学物质编号】 | 24859082 |
| General description【一般描述】 | Conjugated addition of secondary amines, imidazole and pyrazole to methyl 2 methyl 2-acetamidoacrylate in the presence of a catalyst results in the formation of β-Dialkylamino-α-alanine and β-(N-heteroaryl)-α-alanine derivatives. Methyl-2-acetamidoacrylate (M2AA) is an anti-inflammatory agent. The catalytic reaction of methyl 2-acetamidoacrylate with Grignard′s reagents affords α-amino esters. M2AA can form thermosensitive copolymers with methyl acrylate. Methyl ester of 2-acetamidoacrylate . methyl 2-acetamidoacrylate (Me-2-AA) is a di-unsaturated α-amino acid derivative. methyl-2-acetamidoacrylate exihibits anti -inflammatory properties, it is very effective against lipopolysaccharide (LPS)- induced nitric oxide production by RAW 264. |
| Application【应用】 | Methyl 2-acetamidoacrylate can undergo [2+2] cycloaddition (Michael–Dieckmann-type reaction) with ketene diethyl acetal to yield the cyclobutane core. It may be used in rhodium-catalyzed 2-alkenylpyrrole formation. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | 98% |
| bp | 104 ℃/8 mmHg (lit.) |
| mp | 50-52 ℃ (lit.) |
| SMILES string | COC(=O)C(=C)NC(C)=O |
| InChI | 1S/C6H9NO3/c1-4(6(9)10-3)7-5(2)8/h1H2,2-3H3,(H,7,8) |
| InChI key | SMWNFFKPVLVOQQ-UHFFFAOYSA-N |
| packaging【包装】 | 1, 5 g in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H315 - H319 - H335 |
| Precautionary Statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Flash Point(F)【闪点(F)】 | 235.4 °F - closed cup |
| Flash Point(C)【闪点(C)】 | 113 ℃ - closed cup |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
