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2,3-二甲氧基-5-甲基-苯醌

2,3-Dimethoxy-5-methyl-p-benzoquinone
产品编号:3137590
规格:apoptosis inducer
CAS NO:605-94-7
包装规格:1 G,5 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
31375901 G1005
31375905 G3260
产品别名

605-94-7

2,3-二甲氧基-5-甲基-苯醌

2,3-Dimethoxy-5-methyl-p-benzoquinone

Coenzyme Q0

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C9H10O4
Molecular weight
182.17
Beilstein
1640422
EC number【EC 号】
210-100-8
MDL number
MFCD00001595
PubChem Substance ID【PubChem化学物质编号】
24894261
General description【一般描述】
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0 or DMM) is present in all the cells including neural cells.
Application【应用】
Coenzyme Q0 inhibits (via radical quenching) reactions of gamma-irradiation induced homolytic cleavage of O-glycoside bonds in polysaccharides. Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. It is toxic to other cells such as insulin producing cells.
2,3-Dimethoxy-5-methyl-p-benzoquinone has been used:
  • as a tau protein fibrillization inducer to determine the regions of tau involved in the formation of paired helical filaments (PHFs)
  • as a component in buffer B for cytochrome oxidation assay with subsaturating light
  • in the RPMI-1640 medium for 2,3-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT) assay to quantify antifungal activity

Biochem/physiol Actions【生化/生理作用】
2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) interacts with tau protein and aids in the formation of filamentous structure.
产品性质
Quality Level【质量水平】
200
mp
58-60 ℃ (lit.)
storage temp.【储存温度】
2-8℃
SMILES string
COC1=C(OC)C(=O)C(C)=CC1=O
InChI
1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3
InChI key
UIXPTCZPFCVOQF-UHFFFAOYSA-N
packaging【包装】
1, 5 g in glass bottle
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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