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MLR-1023
产品别名
41964-07-2
MLR-1023
CP 26154
5-(3-Methylphenoxy)- 2(1H)-pyrimidinone
NSC 314335
Tolimidone
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H10N2O2 |
| Molecular weight | 202.21 |
| MDL number | MFCD00866900 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825372 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | MLR-1023 has a therapeutic potential to treat type 2 diabetes. MLR-1023 is a potent, orally active, allosteric activator of the non-receptor Src-related Lyn kinase that produces lasting glucose lowering, reduces HbA1c levels, and preserves pancreatic β-cells in db/db mice. MLR-1023 increased insulin receptor sensitivity. MLR-1023 (Tolimidone) is antiulcer agent. |
| Features and Benefits【特点和优势】 | This compound is featured on the InsR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 15 mg/mL (clear solution) |
| storage temp.【储存温度】 | room temp |
| SMILES string | Cc1cccc(OC2=CNC(=O)N=C2)c1 |
| InChI | 1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14) |
| InChI key | HJQILFPVRNHTIG-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
