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Monoclonal Anti-AIFM1 antibody produced in mouse
产品别名
Monoclonal Anti-AIFM1 antibody produced in mouse
COXPD6
PDCD8
AIFM1
MGC111425
AIF
基本信息
NACRES | NA.41 |
General description【一般描述】 | AIFM1 (apoptosis inducing factor mitochondria associated 1) codes for apoptosis-inducing factor 1(AIF). It is located on human chromosome Xq26.1. AIF is a caspase-independent cell death effector. |
Immunogen【免疫原】 | Purified recombinant fragment of human AIF expressed in E.coli. Mouse monoclonal antibody raised against AIF |
Biochem/physiol Actions【生化/生理作用】 | AIFM1 (apoptosis inducing factor mitochondria associated 1) possesses redox activity, which helps in oxidative phosphorylation. In the mitochondria, AIFM1 helps in assembling or maintaining the mitochondrial respiratory complexes I and III. It plays a vital role in apoptosis. This gene is associated with COXPD6 (combined oxidative phosphorylation deficiency, encephalomyopathy, Cowchock syndrome and X-linked deafness with neuropathy. |
Physical form【外形】 | Ascitic fluid containing 0.03% sodium azide. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | ascites fluid |
antibody product type | primary antibodies |
clone【克隆】 | 4E7, monoclonal |
mol wt【分子量】 | 67 kDa |
species reactivity | mouse, monkey, rat, human |
technique(s) | direct ELISA: 1:10,000 flow cytometry: 1:200-1:400 immunohistochemistry: 1:200-1:1,000 indirect immunofluorescence: 1:200-1:1,000 western blot: 1:500-1:2,000 |
isotype【同位素/亚型】 | IgG2b |
NCBI accession no.【NCBI登记号】 | NM_001130846 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... AIF(9131) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |