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Anti-Cathepsin L antibody, Mouse monoclonal
产品编号: | 3142179 |
规格: | clone CPL33/1, purified from hybridoma cell culture |
包装规格: | 200 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Cathepsin L antibody, Mouse monoclonal
Monoclonal Anti-Cathepsin L antibody produced in mouse
Anti-CATL
Anti-MEP
Anti-CTSL
基本信息
MDL number | MFCD01321805 |
NACRES | NA.41 |
General description【一般描述】 | Anti-Cathepsin L antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the hybridoma CPL33/1 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human procathepsin L. Monoclonal Anti-Cathepsin L (mouse IgG1 isotype) is derived from the hybridoma CPL33/1 produced by the fusion of mouse myeloma cells (P3X63Ag8.653) and splenocytes from BALB/c mice immunized with human procathepsin L. |
Specificity【特异性】 | The antibody recognizes the native and denaturated forms of the protein and does not cross react with human cathepsin V. Monoclonal Anti-Cathepsin L specifically recognizes human cathepsin L (∼ 25 kDa) and procathepsin L (∼ 42 kDa). Anti-Cathepsin L antibody epitope resides within amino acids of human cathepsin L (FYKE). |
Immunogen【免疫原】 | human procathepsin L. The antibody epitope resides within amino acids 258-261 of human cathepsin L (FYKE). |
Application【应用】 | Anti-Cathepsin L antibody has been used for immunoblotting. Monoclonal Anti-Cathepsin L antibody produced in mouse is suitable for:
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Biochem/physiol Actions【生化/生理作用】 | Inhibition of the enzyme or the proenzyme by low molecular weight inhibitors or by specific antibodies led to a suppression of the invasive capabilities of malignant cells, or a decline in their ability to form tumors in experimental in vivo and in vitro models. Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis. |
Physical form【外形】 | 0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。 |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | CPL33/1, monoclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~25 kDa (human cathepsin L) antigen ~42 kDa (human pro cathepsin L) |
species reactivity | human |
concentration【浓度】 | ~2 mg/mL |
technique(s) | immunohistochemistry indirect ELISA western blot |
isotype【同位素/亚型】 | IgG1 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CTSL1(1514) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |