Monoclonal Anti-CD326-FITC antibody produced in mouse

NA.44

Epithelial cell adhesion molecule (EpCAM) or cluster of differentiation 326 (CD326), is encoded by the 14kb GA733-2 gene mapped to human chromosome 2p21. Human CD326 expression is restricted to epithelia of colon, small intestine, lung, kidney, thymus, liver, pancreas, stomach. It is also expressed in several cancers, progenitor and stem cells. CD326 is a transmembrane glycoprotein characterized with an ectodomain, one transmembrane domain and a 26 residual cytoplasmic domain.
The mouse monoclonal antibody VU-1D9 recognizes an epitope within EGF-like domain I of CD326 / EpCAM, a marker of epithelial lineages. This antibody strongly stains various normal epithelial cells and carcinomas.

Small cell lung carcinoma cell line H69

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Cluster of differentiation 326 (CD326) is a transmembrane glycoprotein, involved in several cellular functions, such as epithelial-specific intercellular cell–adhesion, cell signaling, migration, proliferation and differentiation. CD326 is a dominant surface antigen mapped on human colon carcinoma. It has potential as a diagnostic marker for several carcinomas, including epithelial ovarian cancer (EOC). CD326 is considered to be a potential target for cancer treatment. CD326 with the help of components of wnt signal transduction pathway plays a vital role in stem cell signaling.

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Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

100

mouse

FITC conjugate

purified immunoglobulin

primary antibodies

VU-1D9, monoclonal

buffered aqueous solution

human

flow cytometry: suitable

IgG1

NM_002354.2

P16422

wet ice

2-8℃

human ... EPCAM(4072)

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10 - Combustible liquids

WGK 2