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Monoclonal Anti-CD4L antibody produced in mouse

产品编号:3142766
规格:clone 9H5A8, purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3142766100 μG5040
产品别名

Monoclonal Anti-CD4L antibody produced in mouse

Anti-CD4 antigen

Anti-CD4 receptor

基本信息
NACRES
NA.41
General description【一般描述】
Cluster of differentiation (CD4) encodes a T-cell surface glycoprotein CD4. In human chromosome, the gene CD4 is localized on 12p13.31.
Immunogen【免疫原】
raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.
Biochem/physiol Actions【生化/生理作用】
Cluster of differentiation (CD4) mutation in single nucleotide causes OKT4 (Leu-3 T4) epitope deficiency. CD4 plays a major role in collateral artery formation by recruiting macrophages at the active site and through triggering the synthesis of arteriogenic cytokines.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
9H5A8, monoclonal
form【形式】
buffered aqueous solution
species reactivity
human, rat, mouse
technique(s)
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.【UniProt登记号】
P01730
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
产品说明
Target description【目标描述】
CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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