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Monoclonal Anti-EMP3 antibody produced in mouse
产品编号: | 3144575 |
规格: | clone 3D4, purified immunoglobulin, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-EMP3 antibody produced in mouse
Anti-YMP
Anti-epithelial membrane protein 3
基本信息
NACRES | NA.41 |
General description【一般描述】 | Epithelial membrane protein-3 (EMP3) belongs to the belongs to the peripheral myelin protein 22 kDa (PMP22) gene family of small hydrophobic membrane glycoproteins. This gene is located on human chromosome 19q13.3. EMP3 codes for a 163 amino-acid protein that has four transmembrane domains. |
Immunogen【免疫原】 | EMP3 (AAH09718, 1 a.a. ~ 163 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSENGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAIHAEEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE |
Biochem/physiol Actions【生化/生理作用】 | Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule that controls apoptosis, differentiation and invasion of cancer cells. This gene may be considered as a tumor suppressor gene in glioma, neuroblastoma, esophageal squamous cell carcinoma (ESCC) cell lines and non-small cell lung cancer (NSCLC). |
Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 3D4, monoclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable indirect ELISA: suitable western blot: 1-5 μg/mL |
isotype【同位素/亚型】 | IgG1κ |
GenBank® accession no. | BC009718 |
UniProt accession no.【UniProt登记号】 | P54852 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... EMP3(2014) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |