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Monoclonal Anti-KCNQ4 antibody produced in mouse
| 产品编号： | 3147330 |
| 规格： | clone 2H6, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-KCNQ4 antibody produced in mouse
Anti-KV7.4
Anti-DFNA2
Anti-potassium voltage-gated channel, KQT-like subfamily, member 4
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 2H6, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | mouse |
| technique(s) | indirect ELISA: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 | IgG3κ |
| GenBank® accession no. | NM_004700 |
| UniProt accession no.【UniProt登记号】 | Q9JK97 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KCNQ4(9132) |
基本信息
| General description【一般描述】 | The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) |
| Immunogen【免疫原】 | KCNQ4 (NP_004691, 596 a.a. ~ 695 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence AREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
| Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
