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Anti-KRAS antibody, Mouse monoclonal
| 产品编号： | 3147495 |
| 规格： | clone KRAS-A582, purified from hybridoma cell culture |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-KRAS antibody, Mouse monoclonal
Anti-K-RAS4B
Anti-K-RAS2A
Anti-K-RAS4A
Anti-C-K-RAS
Anti-K-RAS2B
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| clone【克隆】 | KRAS-A582, monoclonal |
| form【形式】 | aqueous solution |
| mol wt【分子量】 | antigen predicted mol wt 27.9 kDa |
| species reactivity | human |
| technique(s) | western blot: suitable using 1:250-1:500 using HEK-293 cells expressing KRAS |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P01116 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... KRAS(3845) |
基本信息
| General description【一般描述】 | The kirsten rat sarcoma-2 virus oncogene (KRAS) gene is mapped to human chromosome 12p12.1 and belongs to the family of Ras genes. The protein encoded is a small guanosine nucleotide-bound GTPases belonging. |
| Immunogen【免疫原】 | KRAS purified recombinant protein |
| Biochem/physiol Actions【生化/生理作用】 | Mutation in the KRAS gene causes non small-cell lung cancer and promotes tumor initiation, progression and metastasis. Altered KRAS gene also offers resistance to chemotherapy. It is involved in the signal transduction between epidermal growth factor receptor (EGFR) to the nucleus. |
| Physical form【外形】 | Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
