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Monoclonal Anti-Myocardin antibody produced in mouse

产品编号:3148882
规格:~2.0 mg/mL, clone MCR54, purified immunoglobulin
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3148882200 μL4730
产品别名

Monoclonal Anti-Myocardin antibody produced in mouse

Anti-MYOCD

Anti-MYCD

基本信息
NACRES
NA.41
General description【一般描述】
Myocardin (MYOCD) is expressed in the muscles and cardiomyocytes. It is a co-transcriptional factor.
Monoclonal Anti-Myocardin (mouse IgG2b isotype) is derived from the hybridoma MCR54 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human myocardin. Myocardin (MYOCD) is a transcriptional coactivator.
Application【应用】
Monoclonal Anti-Myocardin antibody produced in mouse has been used in western blot analysisimmunofluorescence.
Biochem/physiol Actions【生化/生理作用】
Myocardin (MYOCD) takes part in the differentiation of vascular smooth muscle cells (VSMC). It is a co-factor of serum response factor (SRF) and regulates the activation of those genes which are dependent on SRF. MYOCD forms a complex with SRF on DNA.
Myocardin is a smooth and cardiac muscle-specific transcriptional coactivator of serum response factor (SRF). It regulates the expression of a set of cardiac and smooth muscle-specific genes. Myocardin was implicated in the pathogenesis of atherosclerosis, Alzheimer′s disease, and malignant transformation.
Physical form【外形】
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
MCR54, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen ~150 kDa
species reactivity
human
packaging【包装】
antibody small pack of 25 μL
concentration【浓度】
~2.0 mg/mL
technique(s)
western blot: 2.5-5 μg/mL using HEK-293T cells overexpressing myocardin
isotype【同位素/亚型】
IgG2b
UniProt accession no.【UniProt登记号】
Q8IZQ8
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... MYOCD(93649)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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