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Monoclonal Anti-Nitric Oxide Synthase, Universal antibody produced in mouse
基本信息
| MDL number | MFCD01324876 |
| NACRES | NA.41 |
| Specificity【特异性】 | The antibody reacts with iNOS, eNOS and nNOS from rat and bovine, and with iNOS in induced RAW 264.7 mouse macrophages. In immunoblotting, the antibody detects a band at 130 kDa representing iNOS in samples first induced with IFN (interferon) and LPS (lipopolysaccharides). It also detects a band at 155 kDa in tissues expressing nNOS and a band at 140 kDa in tissues expressing eNOS. The antibody may be used to localize and detect the three isoforms of nitric oxide synthase (NOS): neuronal or brain (nNOS or bNOS), endothelial (eNOS) and inducible (iNOS). |
| Immunogen【免疫原】 | bovine cerebellum NOS. |
| Biochem/physiol Actions【生化/生理作用】 | Neuronal nitric acid synthase (Nos1) in involved in the production of nitric oxide. Mutations in the gene encoding it increases the susceptibility to behavioral dysfunction after an exposure to alcohol in mice. |
| Physical form【外形】 | Ascites fluid containing ≤0.1% sodium azide |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | NOS-3F7-B11-B5, monoclonal |
| species reactivity | rat, bovine, mouse |
| technique(s) | immunohistochemistry (frozen sections): 1:100 western blot: 1:50-1:500 |
| isotype【同位素/亚型】 | IgM |
| UniProt accession no.【UniProt登记号】 | P29476 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Nos1(18125) rat ... Nos1(24598) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
