Monoclonal Anti-Oncostatin M antibody produced in mouse

202-739-6

MFCD01092430

NA.41

Oncostatin M (OSM) is a growth-regulating cytokine produced by the activated T lymphocytes and macrophages. It has a pivotal role in stimulating the production of IL-6 in cultured human endothelial cells. It also facilitates the LDL receptor expression and its uptake by hepatoma cells. Further, OSM can induce synovial fibroblast-like cells to produce urokinase type plasminogen activator. Monoclonal anti-Oncostatin M antibody can be used for neutralizing the biological activity of rhOSM on the human TF-1 cell line. Mouse anti-Oncostatin M antibody reacts specifically with recombinant human OSM. The product has shown no cross-reactivity with recombinant human IL-6, IL-11, CNTF, LIF and recombinant mouse OSM.

The antibody neutralizes the biological activity of recombinant human OSM. Does not cross-react with recombinant human IL-6, IL-11, CNTF, LIF and recombinant mouse OSM.

recombinant human OSM expressed in Escherichia coli.

Monoclonal anti-Oncostatin M antibody can be used in western blotting and capture ELISA.

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (PBS) with 5% trehalose.

Purified using protein A.

100

mouse

unconjugated

purified immunoglobulin

primary antibodies

17001, monoclonal

lyophilized powder

human

indirect ELISA: suitable
neutralization: suitable
western blot: suitable

IgG2a

P13725

−20℃

human ... OSM(5008)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

11 - Combustible Solids

WGK 1

Eyeshields, Gloves, type N95 (US)