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抗-磷酸表皮生长因子受体(pTyr1068)单克隆抗体 小鼠抗
Monoclonal Anti-phospho-Epidermal Growth Factor Receptor (pTyr1068) antibody produced in mouse
| 产品编号： | 3150176 |
| 规格： | clone 338324, purified immunoglobulin, lyophilized powder |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
抗-磷酸表皮生长因子受体(pTyr1068)单克隆抗体 小鼠抗
Monoclonal Anti-phospho-Epidermal Growth Factor Receptor (pTyr1068) antibody produced in mouse
Monoclonal Anti-ERBB
Monoclonal Anti-EGFR
Monoclonal Anti-HER1
Monoclonal Anti-PIG61
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | purified, synthetic phosphopeptide corresponding to residues surrounding tyrosine 1068 of human epidermal growth factor receptor. |
| Biochem/physiol Actions【生化/生理作用】 | EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer. Tyr1068 is a minor autophosphorylation site and enables the binding of EGFR to GAB-1 or Grb2. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 338324, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | human |
| technique(s) | flow cytometry: 5 μg/mL western blot: 1 μg/mL |
| isotype【同位素/亚型】 | IgG2a |
| UniProt accession no.【UniProt登记号】 | P00533 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EGFR(1956) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
