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Monoclonal Anti-Placenta Growth Factor-2 antibody produced in rat
| 产品编号： | 3150368 |
| 规格： | clone 62526, purified immunoglobulin, lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Placenta Growth Factor-2 antibody produced in rat
Anti-PlGF-2
基本信息
| MDL number | MFCD02097209 |
| NACRES | NA.41 |
| General description【一般描述】 | The antibody neutralizes receptor-ligand interaction. The antibody shows no cross-reactivity with recombinant human PlGF and recombinant human VEGF. |
| Immunogen【免疫原】 | purified recombinant mouse placenta growth factor 2 expressed in insect Sf 21 cells. |
| Biochem/physiol Actions【生化/生理作用】 | Placental growth factors (PlGF) are involved in the growth, migration and survival of endothelial cells. All the four isoforms identified are expressed in placenta and umbilical vein endothelial cells. PlGF bind to specific Flt-1 receptors that result in activation and recruitment of dendritic cells, smooth muscle cells and inflammatory cells. PlGF2 has the ability to bind heparin while PlGF1 is a soluble isoform. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 62526, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse |
| technique(s) | indirect ELISA: 0.5-1.0 μg/mL neutralization: suitable western blot: 1-2 μg/mL |
| isotype【同位素/亚型】 | IgG2a |
| UniProt accession no.【UniProt登记号】 | P49764 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Pgf(18654) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
