您的位置:首页 > 产品中心 > Monoclonal Anti-PMS2, (C-terminal) antibody produced in mouse
Monoclonal Anti-PMS2, (C-terminal) antibody produced in mouse
产品编号: | 3150436 |
规格: | clone 4A8, purified immunoglobulin, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-PMS2, (C-terminal) antibody produced in mouse
PMSL2
PMS2CL
HNPCC4
基本信息
NACRES | NA.41 |
General description【一般描述】 | This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. (provided by RefSeq) |
Immunogen【免疫原】 | PMS2 (NP_000526, 763 a.a. ~ 862 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence ERAKLISLPTSKNWTFGPQDVDELIFMLSDSPGVMCRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPWNCPHGRPTMRHIANLGVISQN |
Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 4A8, monoclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~37.11 kDa |
species reactivity | human |
technique(s) | capture ELISA: suitable immunofluorescence: suitable indirect ELISA: suitable |
isotype【同位素/亚型】 | IgG2aκ |
NCBI accession no.【NCBI登记号】 | NM_000535 |
UniProt accession no.【UniProt登记号】 | P54278 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... PMS2(5395) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 1 |