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Anti-Pontin antibody, Mouse monoclonal

产品编号:3150504
规格:clone 5G3-11, purified from hybridoma cell culture
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3150504200 μL4790
产品别名

Anti-Pontin antibody, Mouse monoclonal

Anti-49 kDa TBP-interacting protein

Anti-TAP54-alpha

Anti-nuclear matrix protein 238

Anti-RUVBL1

Anti-NMP 238

Anti-ECP-54

Anti-49 kDa TATA box-binding protein-interacting protein

Anti-RuvB (e coli homolog)-like 1

Anti-INO80 complex subunit H

Anti-RuvB-like 1

Anti-Pontin52

Anti-TIH1

Anti-TIP60-associated protein 54-alpha

Anti-54 kDa erythrocyte cytosolic protein

Anti-TIP49

Anti-RVB1

Anti-TIP49A

基本信息
NACRES
NA.41
General description【一般描述】
Monoclonal Anti-Pontin (mouse IgG1 isotype) is derived from the hybridoma 5G3-11 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human pontin fusion protein. Pontin and reptin are two related members of the AAA+ (ATPases associated with diverse cellular activities) family of ATPases. Pontin and reptin share some homology to the bacterial RuvB gene.
Immunogen【免疫原】
human Pontin fusion protein
Application【应用】
Monoclonal Anti-Pontin antibody produced in mouse has been used in:
  • western blotting
  • immunoprecipitation
  • ChIP-sequencing
  • immunohistochemistry
  • immunofluorescence
  • RNA immunoprecipitation

Biochem/physiol Actions【生化/生理作用】
Pontin and Reptin are associated with several chromatin-remodeling complexes and are involved in multiple biological processes including chromatin remodeling, DNA damage repair, transcriptional regulation, telomerase activity, apoptosis and cancer metastasis. Both proteins are also involved in cellular transformation by beta-catenin and c-myc through their chromatin remodeling function.
Physical form【外形】
Solution in 0.01 M phosphate buffered saline, 7.4 pH, containing 15 mM sodium azide
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified from hybridoma cell culture
antibody product type
primary antibodies
clone【克隆】
5G3-11, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
~50 kDa
species reactivity
monkey, human, canine
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
indirect immunofluorescence: suitable
western blot: 1:1,000-1:2,000 using whole extracts of human HEK-293T or MCF-7 cells
isotype【同位素/亚型】
IgG
UniProt accession no.【UniProt登记号】
Q9Y265
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... RUVBL1(8607)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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