Anti-PVRL4 antibody, Mouse monoclonal

NA.41

Monoclonal Anti-Nectin-4/PVRL4 (mouse IgG1 isotype) is derived from the hybridoma R2.525.2 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human nectin4-Fc recombinant protein. Nectin-4 belongs to the family of Nectins. It forms homo-cis-dimers and then homo- or hetero-trans-dimers through the extracellular region in a Ca²⁺-independent manner. Nectin-4 is expressed in placenta, ductal breast carcinoma and lung adenocarcinomas. It is one of the plasma membrane components of adherens junctions.

human Nectin4/Fc recombinant protein

Monoclonal Anti-PVRL4 antibody produced in mouse has been used in immunocytochemistry and flow cytometry.

Nectin-4 is involved in cell adhesion through trans homophilic and heterophilic interactions. Mutations in this gene are associated with ectodermal dysplasia-syndactyly syndrome type 1.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

200

mouse

unconjugated

purified from hybridoma cell culture

primary antibodies

N4.101.10, monoclonal

buffered aqueous solution

human

~1.0 mg/mL

flow cytometry: 5-10 μg/test using using 1x10⁶ MDA-MB-231 cells
immunocytochemistry: 2.5-5 μg/mL using using MDA-MB-231 cells

IgG1

dry ice

−20℃

human ... PVRL4(81607)

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12 - Non Combustible Liquids