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Monoclonal Anti-RANTES antibody produced in rat
| 产品编号： | 3151214 |
| 规格： | clone 53405.111, purified immunoglobulin, lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD01635727 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | purified, E. coli-derived, recombinant mouse RANTES. |
| Biochem/physiol Actions【生化/生理作用】 | RANTES (Regulated upon Activation, Normal T cell Expressed and Secreted; CCL5) is a chemokine that brings T cells, monocytes, eosinophils, NK cells, dendritic cells and mast cells to the site of infection or inflammation. RANTES has an unusual kinetic profile and is secreted 3-5 days after the activation of the T cells. It also exhibits antimicrobial activity by inducing the production of nitric oxide in macrophages. The expression of RANTES is regulated mainly by JAK/STAT and NF-κB pathways. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose pH 7.4. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 53405.111, monoclonal |
| form【形式】 | lyophilized powder |
| purified by【纯化方式】 | using protein G |
| species reactivity | mouse |
| technique(s) | immunocytochemistry: 8-25 μg/mL using mouse splenocytes neutralization: suitable |
| isotype【同位素/亚型】 | IgG2a |
| UniProt accession no.【UniProt登记号】 | P30882 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Ccl5(20304) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
