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Monoclonal Anti-RB1 antibody produced in mouse
产品别名
Monoclonal Anti-RB1 antibody produced in mouse
p105-Rb
pp110
RB
pRb
OSRC
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The gene encoding Retinoblastoma-associated protein (RB1) is a tumor suppressor gene localized on human chromosome 13q14.2. |
| Immunogen【免疫原】 | Purified recombinant fragment of human RB expressed in E.coli. Mouse monoclonal antibody raised against RB |
| Biochem/physiol Actions【生化/生理作用】 | Retinoblastoma-associated protein (RB1) modulates the cell cycle. It acts as a repressor of transcription mediated by E2 factor (E2F) and influences transcriptional silencing. RB1 modulates mitochondrial activities and has a role in the organisation of heterochromatin. Mutations in the gene encoding this protein have been associated with childhood retinoblastoma. |
| Physical form【外形】 | Ascitic fluid containing 0.03% sodium azide. |
产品性质
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 7E4B8, monoclonal |
| species reactivity | human |
| technique(s) | direct ELISA: 1:10,000 immunohistochemistry: 1:200-1:1,000 western blot: 1:500-1:2,000 |
| isotype【同位素/亚型】 | IgG1 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RB(5925) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
