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Monoclonal Anti-RET antibody produced in mouse
产品别名
Monoclonal Anti-RET antibody produced in mouse
RET
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The RET (rearranged during transfection) proto-oncogene is mapped to human chromosome 10q11. It has two isoforms, namely RET9 and RET51 with unique C-terminal tail sequences. RET is made of 20 exons and 21 introns. |
| Immunogen【免疫原】 | Purified recombinant fragment of RET (aa896-1063) expressed in E.coli. Mouse monoclonal antibody raised against RET |
| Biochem/physiol Actions【生化/生理作用】 | The RET (rearranged during transfection) is involved in signal transduction pathways related to cell proliferation and differentiation. Mutations in RET gene results in medullary thyroid carcinoma and Hirschsprung′s disease. It is involved in normal development and cancer. The isoforms of RET provides distinct protein complexes to promote signals. |
| Physical form【外形】 | Ascitic fluid containing 0.03% sodium azide. |
产品性质
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 8D10C9, monoclonal |
| species reactivity | human |
| technique(s) | direct ELISA: 1:10,000 western blot: 1:500-1:2,000 |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | P07949 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RET(5979) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
