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Monoclonal Anti-RHOT1 antibody produced in mouse
产品编号: | 3151475 |
规格: | Prestige Antibodies® Powered by Atlas Antibodies, clone CL1095, purified immunoglobulin, buffered aqueous glycerol solution |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-RHOT1 antibody produced in mouse
ARHT1
MIRO-1
FLJ11040
产品性质
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | CL1095, monoclonal |
product line【产品线】 | Prestige Antibodies® Powered by Atlas Antibodies |
form【形式】 | buffered aqueous glycerol solution |
species reactivity | human |
packaging【包装】 | antibody small pack of 25 μL |
technique(s) | immunohistochemistry: 1:200- 1:500 |
isotype【同位素/亚型】 | IgG1 |
Ensembl | human accession no.【基因组数据库 |人类登记号】 | ENSG00000126858 |
UniProt accession no.【UniProt登记号】 | Q8IXI2 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... RHOT1(55288) |
基本信息
General description【一般描述】 | Miro1/RHOT1 (ras homolog family member T1) is an outer mitochondrial membrane (OMM) protein. It has a transmembrane domain, two GTPase domains and two Ca2+-sensing EF-hand domains. RHOT1 is located on human chromosome 17q11. |
Immunogen【免疫原】 | ras homolog family member T1, recombinant protein epitope signature tag (PrEST) Sequence THIVDYSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIE Epitope Binds to an epitope located within the peptide sequence ERTDKDSRLP as determined by overlapping synthetic peptides. |
Application【应用】 | Monoclonal Anti-RHOT1 antibody has been used in Immunoprecipitation. |
Biochem/physiol Actions【生化/生理作用】 | Miro1/RHOT1 (ras homolog family member T1) regulates mitochondrial trafficking and distribution. The Rho GTPase Miro-1 plays a crucial role in the modulation of mitochondrial morphogenesis and acts as a calcium-dependent sensor for the control of mitochondrial motility. |
Features and Benefits【特点和优势】 | Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section. Every Prestige Antibody is tested in the following ways:
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Linkage【联系】 | Corresponding Antigen APREST71907. |
Physical form【外形】 | Phospate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide |
Legal Information【法律信息】 | Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10;12 - Combustible liquids;Non Combustible Liquids |
WGK | WGK 1 |