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Monoclonal Anti-Rin/Rit2 antibody produced in mouse
| 产品编号： | 3151486 |
| 规格： | ~1 mg/mL, clone 18G4(27G2), purified immunoglobulin, buffered aqueous glycerol solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Rin/Rit2 antibody produced in mouse
Anti-Ras-like without CAAX 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Rin/Rit2 (Ras-like without CAAX 2) belongs to the Ras superfamily of small guanosine triphosphatases. In human, it is expressed in several neurons whereas in mouse, it is expressed in the ganglion cell layer and inner nuclear layer of the retina. It is located on human chromosome 18q12.3. |
| Immunogen【免疫原】 | recombinant human Rin. |
| Biochem/physiol Actions【生化/生理作用】 | Aberrations in Rin/Rit2 (Ras-like without CAAX 2) causes parkinson′s disease. It participates in neurotrophin signaling. It trigger ERK (extracellular signal-regulated kinase) and p38 MAP (mitogen-activated protein) kinase signaling to promote differentiation. |
| Physical form【外形】 | Solution in 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, and 3 mM sodium azide. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 18G4(27G2), monoclonal |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | antigen ~36 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | western blot: 1:5,000 using HEK293 cells expressing HA-tagged Rit |
| isotype【同位素/亚型】 | IgG2b |
| UniProt accession no.【UniProt登记号】 | Q99578 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RIT2(6014) mouse ... Rit2(19762) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
