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Anti-Sumo-1 antibody, Rat monoclonal

产品编号:3152890
规格:clone 4D12, purified from hybridoma cell culture
包装规格:200 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3152890200 μL5040
产品别名

Anti-Sumo-1 antibody, Rat monoclonal

Anti-small ubiquitin-like modifier 1

Anti-DAP1

Anti-SMT3H3 SMT3C

Anti-SMT3 suppressor of mif two 3 homolog 1 SENTRIN PIC1 OROFACIAL CLEFT 10, INCLUDED; OFC10

SUMO-1

Anti-GMP1

SUMO1

Anti-ubiquitin-like 1

Monoclonal Anti-Sumo-1

Anti-OFC10 CLEFT LIP WITH OR WITHOUT CLEFT PALATE, NONSYNDROMIC, 10

Anti-UBL1, SMT3, YEAST, HOMOLOG 3

基本信息
MDL number
MFCD02096449
NACRES
NA.41
General description【一般描述】
SUMO1 (small ubiquitin-related modifier), also called as Pic1 (inner centromere protein-related protein), Ubl1 (ubiquitin-like protein), hSmt3 (human homolog 3), or sentrin, is mainly expressed in the nucleus. The gene encoding SUMO1 is mapped to human chromosome 2q33. SUMO1 belongs to ubiquitin-like protein family and it consists of 101 amino acids.
Monoclonal Anti-Sumo-1 (rat IgG2a isotype) is derived from the hybridoma 4D12 produced by the fusion of mouse myeloma cells (SP2/0) and splenocytes from rat immunized with a fusion protein of human SUMO1.
Immunogen【免疫原】
fusion protein of human SUMO1
Application【应用】
Monoclonal Anti-Sumo-1 has been used in immunocytochemistry.
Monoclonal Anti-Sumo-1 has been used in western blotting.
Biochem/physiol Actions【生化/生理作用】
Suppressing SUMO1 (small ubiquitin-related modifier) inhibits multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It is also implicated in mitochondrial fission.
Sumo-1 interacts with dsDNA and competes with other protein-DNA interactions.
Physical form【外形】
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
产品性质
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified from hybridoma cell culture
antibody product type
primary antibodies
clone【克隆】
4D12, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
~12 kDa
species reactivity
mouse, human, rat
concentration【浓度】
~1.0 mg/mL
technique(s)
immunocytochemistry: suitable
western blot: 2-4 μg/mL using HeLa cell extracts
isotype【同位素/亚型】
IgG2a
UniProt accession no.【UniProt登记号】
P63165
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SUMO1(7341)
mouse ... Sumo1(22216)
rat ... Sumo1(301442)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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