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N,N-Dimethylsphingosine
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3160771 | 5 MG | 1380 | |||
| 3160771 | 25 MG | 5100 |
产品别名
119567-63-4
N,N-Dimethylsphingosine
D-Erythro-N,N-Dimethylsphingosine
DMS
(2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol
Dimethylsphingosine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H41NO2 |
| Molecular weight | 327.55 |
| MDL number | MFCD02259309 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825316 |
| Application【应用】 | N,N-Dimethylsphingosine has been used as an internal standard in liquid chromatography with tandem mass spectrometry (LC-MS-MS) for psychosine quantification in fibroblasts from twitcher (TWI) and wild type mice. It has also been used as an inhibitor of sphingosine kinase (SphK) to investigate the role of SphK in enhancing lipopolysaccharide (LPS)-mediated chemokine expression. |
| Biochem/physiol Actions【生化/生理作用】 | N,N-Dimethylsphingosine (DMS) is an endogenous metabolite of sphingosine produced in various tissues and tumor cell lines. N,N-Dimethylsphingosine is a potent inhbitor of sphingosine kinase. DMS levels are elevated in the spinal cord, and contributes to allodynia, in a transected-nerve model of neuropathic pain. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | film |
| color【颜色】 | colorless |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC[C@@](N(C)C)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC |
| InChI | 1S/C20H41NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(18-22)21(2)3/h16-17,19-20,22-23H,4-15,18H2,1-3H3/b17-16+/t19-,20+/m0/s1 |
| InChI key | YRXOQXUDKDCXME-YIVRLKKSSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
