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N-Desmethyltamoxifen HCl
产品别名
15917-65-4
N-Desmethyltamoxifen HCl
(Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine
ICI 55,548
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H27NO·HCl |
| Molecular weight | 393.95 |
| MDL number | MFCD03423594 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798889 |
| NACRES | NA.77 |
| Application【应用】 | N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes. |
| Biochem/physiol Actions【生化/生理作用】 | N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor. |
| Features and Benefits【特点和优势】 | This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| sterility【无菌性】 | non-sterile |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| technique(s) | inhibition assay: suitable |
| solubility【溶解性】 | DMSO: ≥20 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | room temp |
| SMILES string | Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3 |
| InChI | 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-; |
| InChI key | GMLHJWZEYLTNJW-BJFQDICYSA-N |
| packaging【包装】 | 5 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS08,GHS09 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H350 - H360 - H410 |
| Precautionary Statements | P201 - P273 - P308 + P313 |
| Hazard Classifications【危险分类】 | Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges |
