您的位置：首页 > 产品中心 > 105816-04-4， 那格列奈
那格列奈
Nateglinide
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3172725 | 10 MG | 2720 |
产品别名
105816-04-4
那格列奈
Nateglinide
Fastic
N-[(trans-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine
Starlix
Starsis
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H27NO3 |
| Molecular weight | 317.42 |
| MDL number | MFCD00875706 |
| PubChem Substance ID【PubChem化学物质编号】 | 329818636 |
| Biochem/physiol Actions【生化/生理作用】 | Nateglinide is a Kir6.2/SUR1 channel inhibitor and antidiabetic. It is selective for the SUR1 subtype, which is found on pancreatic islet cells. Nateglinide evokes KATP channel-dependent insulin secretion (50-200 μM) in the absence and presence of insulin. Nateglinide is a short-acting insulin secretagogue useful in treating type 2 diabetes. It is an insulinotropic agent effective for postprandial hyperglycemia. Nateglinide restores prandial insulin levels in a glucose-dependent manner. |
| Features and Benefits【特点和优势】 | This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | DMSO: >5 mg/mL H2O: insoluble |
| originator【创始人】 | Novartis |
| storage temp.【储存温度】 | room temp |
| SMILES string | CC(C)[C@@H]1CC[C@H](CC1)C(=O)N[C@H](Cc2ccccc2)C(O)=O |
| InChI | 1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1 |
| InChI key | OELFLUMRDSZNSF-BRWVUGGUSA-N |
| Gene Information | human ... ABCC8(6833), KCNJ11(3767) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
