神经氨酸酶活性检测试剂盒

NA.84

Neuraminidase, also known as Sialidase, is an enzyme that hydrolyzes terminal sialic acid residues on poly-saccharide chains. It is predominantly expressed in microorganisms such as bacteria and viruses. Cleavage of sialic acid residues by neuraminidase is believed to play several roles in infection by influenza viruses. It is thought to assist in the penetration of mucosal linings, the invasion of target cells, the elution of progeny viruses from infected cells, and the prevention of self-aggregation. Thus, neuraminidase is an important target for influenza drug development and simple, direct, and automation-ready procedures for measuring neuraminidase activity find wide applications in research and drug discovery.

兼容高通量的操作系统。

In this assay, neuraminidase activity is determined by an enzymatic assay in which sialic acid released by neuraminidase results in a colorimetric (570 nm)/fluorometric (λex = 530/λem = 585 nm) product directly proportional to neuraminidase activity in the sample. The linear detection range at 37 ℃ is 0.1-10 units/L for colorimetric assays and 0.01-2 units/L for fluorometric assays.

sufficient for 100 colorimetric or fluorometric tests

colorimetric
fluorometric

dry ice

−20℃

适用于生物样品中的神经氨酸酶活性检测，可用于筛选神经氨酸酶抑制剂。

GHS08

Danger

H317 - H334

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Resp. Sens. 1 - Skin Sens. 1

10 - Combustible liquids

WGK 3