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烟酸
Nicotinic Acid
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3175061 | 100 G | 3340 |
产品别名
59-67-6
烟酸
Nicotinic Acid
Pellagra preventive factor
Niacin
Pyridine-3-carboxylic Acid
Vitamin B3
3-Picolinic acid
尼亚生
抗糙皮病因子
维生素 B3
3-吡啶甲酸
吡啶-3-羧酸
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C6H5NO2 |
Molecular weight | 123.11 |
Beilstein | 109591 |
EC number【EC 号】 | 200-441-0 |
MDL number | MFCD00006391 |
PubChem Substance ID【PubChem化学物质编号】 | 24897734 |
NACRES | NA.21 |
General description【一般描述】 | Nicotinic acid, also referred to as niacin or as vitamin B3, is a water-soluble vitamin. Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat. |
Application【应用】 | Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity. |
Biochem/physiol Actions【生化/生理作用】 | Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia. It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides. Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn′s disease Deficiency also impacts DNA repair and also leads to skin and gastrointestinal disorder, pellagra. Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | synthetic (organic) |
agency | USP/NF meets USP testing specifications |
Assay【测定】 | 99.0-101.0% dry basis |
form【形式】 | powder |
color【颜色】 | white |
mp | 236-239 ℃ (lit.) |
application(s) | pharmaceutical (small molecule) |
SMILES string | OC(=O)c1cccnc1 |
InChI | 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9) |
InChI key | PVNIIMVLHYAWGP-UHFFFAOYSA-N |
Gene Information | human ... CYP1A2(1544) rat ... Chrnb2(54239) |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H319 |
Precautionary Statements | P280 - P305 + P351 + P338 - P337 + P313 |
Hazard Classifications【危险分类】 | Eye Irrit. 2 |
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 1 |
Flash Point(F)【闪点(F)】 | 379.4 °F - closed cup |
Flash Point(C)【闪点(C)】 | 193 ℃ - closed cup |
Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |